4Z68
Hybrid structural analysis of the Arp2/3 regulator Arpin identifies its acidic tail as a primary binding epitope
Summary for 4Z68
Entry DOI | 10.2210/pdb4z68/pdb |
Descriptor | Tankyrase-2, GLU-ILE-ARG-GLU-GLN-GLY-ASP-GLY-ALA-GLU-ASP-GLU, SULFATE ION, ... (4 entities in total) |
Functional Keywords | cell migration, arpin, arp 2/3, actin polymerization, protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: Q9H2K2 |
Total number of polymer chains | 2 |
Total formula weight | 18533.68 |
Authors | Fetics, S.K.,Campanacci, V.,Dang, I.,Gautreau, A.,Cherfils, J. (deposition date: 2015-04-04, release date: 2015-12-30, Last modification date: 2024-01-10) |
Primary citation | Fetics, S.,Thureau, A.,Campanacci, V.,Aumont-Nicaise, M.,Dang, I.,Gautreau, A.,Perez, J.,Cherfils, J. Hybrid Structural Analysis of the Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope. Structure, 24:252-260, 2016 Cited by PubMed: 26774128DOI: 10.1016/j.str.2015.12.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.859 Å) |
Structure validation
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