4Z68

Hybrid structural analysis of the Arp2/3 regulator Arpin identifies its acidic tail as a primary binding epitope

4Z68 の概要

• エントリーDOI: 10.2210/pdb4z68/pdb
• 分子名称: Tankyrase-2, GLU-ILE-ARG-GLU-GLN-GLY-ASP-GLY-ALA-GLU-ASP-GLU, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: cell migration, arpin, arp 2/3, actin polymerization, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm: Q9H2K2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18533.68

構造登録者

Fetics, S.K.,Campanacci, V.,Dang, I.,Gautreau, A.,Cherfils, J. (登録日: 2015-04-04, 公開日: 2015-12-30, 最終更新日: 2024-01-10)

• 主引用文献: Fetics, S.,Thureau, A.,Campanacci, V.,Aumont-Nicaise, M.,Dang, I.,Gautreau, A.,Perez, J.,Cherfils, J.; Hybrid Structural Analysis of the Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope.; Structure, 24:252-260, 2016; PubMed: 26774128; DOI: 10.1016/j.str.2015.12.001

実験手法

X-RAY DIFFRACTION (1.859 Å)