4Z34
Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO9780307
Summary for 4Z34
Entry DOI | 10.2210/pdb4z34/pdb |
Related | 4Z35 4Z36 |
Descriptor | Lysophosphatidic acid receptor 1, Soluble cytochrome b562, {1-[(2S,3S)-2-(2,3-dihydro-1H-inden-2-ylmethyl)-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)-1 H-pyrrol-3-yl}acetic acid, (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate (3 entities in total) |
Functional Keywords | human lysophosphatidic acid receptor 1 (lpa1), g-protein coupled receptor (gpcr), membrane protein, antagonist, endogenous ligand, psi-biology, structural genomics, gpcr network, lipidic cubic phase (lcp), compound design, polypharmacology, lipid receptor, transport protein-inhibitor complex, transport protein/inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell surface : Q92633 |
Total number of polymer chains | 1 |
Total formula weight | 53436.25 |
Authors | Chrencik, J.E.,Roth, C.B.,Terakado, M.,Kurata, H.,Omi, R.,Kihara, Y.,Warshaviak, D.,Nakade, S.,Asmar-Rovira, G.,Mileni, M.,Mizuno, H.,Griffith, M.T.,Rodgers, C.,Han, G.W.,Velasquez, J.,Chun, J.,Stevens, R.C.,Hanson, M.A.,GPCR Network (GPCR) (deposition date: 2015-03-30, release date: 2015-06-03, Last modification date: 2023-09-27) |
Primary citation | Chrencik, J.E.,Roth, C.B.,Terakado, M.,Kurata, H.,Omi, R.,Kihara, Y.,Warshaviak, D.,Nakade, S.,Asmar-Rovira, G.,Mileni, M.,Mizuno, H.,Griffith, M.T.,Rodgers, C.,Han, G.W.,Velasquez, J.,Chun, J.,Stevens, R.C.,Hanson, M.A. Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell, 161:1633-1643, 2015 Cited by PubMed: 26091040DOI: 10.1016/j.cell.2015.06.002 PDB entries with the same primary citation |
Experimental method |
Structure validation
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