4Z1F
Crystal structure of human Trap1 with PU-H71
Summary for 4Z1F
Entry DOI | 10.2210/pdb4z1f/pdb |
Related | 4z1g 4z1h 4z1i |
Descriptor | Heat shock protein 75 kDa, mitochondrial, 8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE (3 entities in total) |
Functional Keywords | mitochondrial hsp90, chaperone |
Biological source | Homo sapiens (Human) |
Cellular location | Mitochondrion : Q12931 |
Total number of polymer chains | 1 |
Total formula weight | 57934.46 |
Authors | |
Primary citation | Lee, C.,Park, H.K.,Jeong, H.,Lim, J.,Lee, A.J.,Cheon, K.Y.,Kim, C.S.,Thomas, A.P.,Bae, B.,Kim, N.D.,Kim, S.H.,Suh, P.G.,Ryu, J.H.,Kang, B.H. Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 J.Am.Chem.Soc., 137:4358-4367, 2015 Cited by PubMed: 25785725DOI: 10.1021/ja511893n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.703 Å) |
Structure validation
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