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4YWP

Sucrose Binding Site in genetically engineered Carbonic anhydrase IX

Summary for 4YWP
Entry DOI10.2210/pdb4ywp/pdb
Related4ZAO
Related PRD IDPRD_900003
DescriptorCarbonic anhydrase 2, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ZINC ION, ... (4 entities in total)
Functional Keywordsalpha-carbonic anhydrase, ca ix mimic, sucrose, lyase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm : P00918
Total number of polymer chains1
Total formula weight29252.17
Authors
Pinard, M.A.,Aggarwal, M. (deposition date: 2015-03-20, release date: 2015-10-14, Last modification date: 2023-09-27)
Primary citationPinard, M.A.,Aggarwal, M.,Mahon, B.P.,Tu, C.,McKenna, R.
A sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX.
Acta Crystallogr F Struct Biol Commun, 71:1352-1358, 2015
Cited by
PubMed: 26457530
DOI: 10.1107/S2053230X1501239X
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.45 Å)
Structure validation

217705

數據於2024-03-27公開中

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