4YWA

Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA

4YWA の概要

• エントリーDOI: 10.2210/pdb4ywa/pdb
• 分子名称: PA-I galactophilic lectin, CALCIUM ION, (2R,3R,4S,5R,6R,2'R,3'R,4'S,5'R,6'R)-2,2'-([(2R,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2,5-diyl]bis{1H-1,2,3-triazole-1,4-diyl[(2S,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2,5-diyl]-1H-1,2,3-triazole-1,4-diylmethanediyloxy})bis[6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol], ... (4 entities in total)
• 機能のキーワード: galactosides, lectins, sugar binding protein
• 由来する生物種: Pseudomonas aeruginosa
• 細胞内の位置: Cytoplasm: Q05097
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 53426.80

構造登録者

Visini, R.,Jin, X.,Michaud, G.,Bergmann, M.,Gillon, E.,Imberty, A.,Stocker, A.,Darbre, T.,Pieters, R.,Reymond, J.-L. (登録日: 2015-03-20, 公開日: 2015-09-09, 最終更新日: 2024-01-10)

• 主引用文献: Visini, R.,Jin, X.,Bergmann, M.,Michaud, G.,Pertici, F.,Fu, O.,Pukin, A.,Branson, T.R.,Thies-Weesie, D.M.,Kemmink, J.,Gillon, E.,Imberty, A.,Stocker, A.,Darbre, T.,Pieters, R.J.,Reymond, J.L.; Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA.; Acs Chem.Biol., 10:2455-2462, 2015; PubMed: 26295304; DOI: 10.1021/acschembio.5b00302

実験手法

X-RAY DIFFRACTION (1.192 Å)