4YW3
Crystal Structure of Streptococcus pneumoniae NanC, complex with Neu5Ac and Neu5Ac2en following soaking with Neu5Ac2en
Summary for 4YW3
Entry DOI | 10.2210/pdb4yw3/pdb |
Descriptor | Neuraminidase C, PHOSPHATE ION, N-acetyl-alpha-neuraminic acid, ... (6 entities in total) |
Functional Keywords | sialidase, neuraminidase, beta-propeller, cbm40, hydrolase |
Biological source | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) |
Total number of polymer chains | 2 |
Total formula weight | 149238.27 |
Authors | Owen, C.D.,Lukacik, P.,Potter, J.A.,Walsh, M.,Taylor, G.L. (deposition date: 2015-03-20, release date: 2015-09-23, Last modification date: 2024-05-08) |
Primary citation | Owen, C.D.,Lukacik, P.,Potter, J.A.,Sleator, O.,Taylor, G.L.,Walsh, M.A. Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290:27736-27748, 2015 Cited by PubMed: 26370075DOI: 10.1074/jbc.M115.673632 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report