4YQI

Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds

4YQI の概要

• エントリーDOI: 10.2210/pdb4yqi/pdb
• 分子名称: tRNA (guanine-N(1)-)-methyltransferase, (4-amino-1,2,5-oxadiazol-3-yl)[4-(pyridin-2-ylmethyl)piperazin-1-yl]methanone (3 entities in total)
• 機能のキーワード: trmd, sam-binding, knot, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
• 細胞内の位置: Cytoplasm : P43912
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28672.88

構造登録者

Elkins, P.A.,Bonnette, W.G.,Madauss, K.P.,Stuckey, J.A. (登録日: 2015-03-13, 公開日: 2016-03-16, 最終更新日: 2023-09-27)

• 主引用文献: Elkins, P.A.,Bonnette, W.G.,Williams, S.P.,Stuckey, J.A.; Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds; To Be Published,

実験手法

X-RAY DIFFRACTION (1.92 Å)