4YPI

Structure of Ebola virus nucleoprotein N-terminal fragment bound to a peptide derived from Ebola VP35

4YPI の概要

• エントリーDOI: 10.2210/pdb4ypi/pdb
• 分子名称: Nucleoprotein, Polymerase cofactor VP35 (2 entities in total)
• 機能のキーワード: protein complex., ebola virus, nucleoprotein, vp35, rna binding protein, structural genomics, center for structural genomics of infectious diseases, csgid
• 由来する生物種: Zaire ebolavirus (strain Mayinga-76) (ZEBOV); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 168161.11

構造登録者

Leung, D.W.,Borek, D.M.,Binning, J.M.,Otwinowski, Z.,Amarasinghe, G.K.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2015-03-13, 公開日: 2015-04-08, 最終更新日: 2019-12-04)

• 主引用文献: Leung, D.W.,Borek, D.,Luthra, P.,Binning, J.M.,Anantpadma, M.,Liu, G.,Harvey, I.B.,Su, Z.,Endlich-Frazier, A.,Pan, J.,Shabman, R.S.,Chiu, W.,Davey, R.A.,Otwinowski, Z.,Basler, C.F.,Amarasinghe, G.K.; An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.; Cell Rep, 11:376-389, 2015; PubMed: 25865894; DOI: 10.1016/j.celrep.2015.03.034

実験手法

X-RAY DIFFRACTION (3.71 Å)