4YLQ

Crystal Structure of a FVIIa-Trypsin Chimera (FT) in Complex with Soluble Tissue Factor

4YLQ の概要

• エントリーDOI: 10.2210/pdb4ylq/pdb
• 関連するPDBエントリー: 4Z6A
• 分子名称: Coagulation factor VII, Tissue factor, alpha-D-xylopyranose-(1-3)-alpha-D-xylopyranose-(1-3)-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: trypsin-fold, protein-protein complex, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 73028.81

構造登録者

Sorensen, A.B.,Svensson, L.A.,Gandhi, P.S. (登録日: 2015-03-05, 公開日: 2015-12-30, 最終更新日: 2024-01-10)

• 主引用文献: Sorensen, A.B.,Madsen, J.J.,Svensson, L.A.,Pedersen, A.A.,stergaard, H.,Overgaard, M.T.,Olsen, O.H.,Gandhi, P.S.; Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity.; J.Biol.Chem., 291:4671-4683, 2016; PubMed: 26694616; DOI: 10.1074/jbc.M115.698613

実験手法

X-RAY DIFFRACTION (1.4 Å)