4YIL

OYE1 W116A COMPLEXED WITH (Z)-METHYL 3-CYANO-3-(4-FLUOROPHENYL)ACRYLATE IN A NON PRODUCTIVE BINDING MODE

Summary for 4YIL

• Entry DOI: 10.2210/pdb4yil/pdb
• Related: 4GBU
• Descriptor: NADPH dehydrogenase 1, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: oxidoreductase, catalytic activity, fmn binding
• Biological source: Saccharomyces pastorianus (Lager yeast)
• Total number of polymer chains: 1
• Total formula weight: 45275.78

Authors

Santangelo, S.,Brenna, E.,Stewart, J.D.,Powell III, R.W. (deposition date: 2015-03-02, release date: 2016-01-20, Last modification date: 2024-01-10)

• Primary citation: Brenna, E.,Crotti, M.,Gatti, F.G.,Monti, D.,Parmeggiani, F.,Powell III, R.W.,Santangelo, S.,Stewart, J.D.; Opposite Enantioselectivity in the Bioreduction of (Z)-beta-Aryl-beta-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R)- and (S)-beta-Aryl-gamma-lactams; Adv.Synth.Catal., 357:1849-1860., 2015; DOI: 10.1002/adsc.201500206

Experimental method

X-RAY DIFFRACTION (1.461 Å)