4YIF

Crystal structure of Rv0880

Summary for 4YIF

Entry DOI	10.2210/pdb4yif/pdb
Descriptor	MarR family protein Rv0880 (2 entities in total)
Functional Keywords	marr family, dna binding protein, repressor, mycobacterium tuberculosis
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	6
Total formula weight	107198.52
Authors	Gao, Y.R.,Feng, N.,Li, D.F.,Bi, L.J. (deposition date: 2015-03-02, release date: 2015-06-10, Last modification date: 2023-11-08)
Primary citation	Gao, Y.R.,Feng, N.,Chen, T.,Li, D.F.,Bi, L.J. Structure of the MarR family protein Rv0880 from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.F, 71:741-745, 2015 Cited by PubMed Abstract: Rv0880 from the pathogen Mycobacterium tuberculosis is classified as a MarR family protein in the Pfam database. It consists of 143 amino acids and has an isoelectric point of 10.9. Crystals of Rv0880 belonged to space group P1, with unit-cell parameters a = 54.97, b = 69.60, c = 70.32 Å, α = 103.71, β = 111.06, γ = 105.83°. The structure of the MarR family transcription regulator Rv0880 was solved at a resolution of 2.0 Å with an R(cryst) and R(free) of 21.2 and 24.9%, respectively. The dimeric structure resembles that of other MarR proteins, with each subunit comprising a winged helix-turn-helix domain connected to an α-helical dimerization domain. PubMed: 26057805 DOI: 10.1107/S2053230X15007281 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.002 Å)

Structure validation