4YEA

Crystal structure of cisplatin bound to a human copper chaperone (dimer) - new refinement

4YEA の概要

• エントリーDOI: 10.2210/pdb4yea/pdb
• 分子名称: Copper transport protein ATOX1, COPPER (II) ION, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: re-refinement of 3iwx, cisplatin, platinum, metal-binding, metal transport
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 14914.64

構造登録者

Shabalin, I.G.,Dauter, Z.,Jaskolski, M.,Minor, W.,Wlodawer, A. (登録日: 2015-02-23, 公開日: 2015-03-18, 最終更新日: 2023-09-27)

• 主引用文献: Shabalin, I.,Dauter, Z.,Jaskolski, M.,Minor, W.,Wlodawer, A.; Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.; Acta Crystallogr.,Sect.D, 71:1965-1979, 2015; PubMed: 26327386; DOI: 10.1107/S139900471500629X

実験手法

X-RAY DIFFRACTION (2.14 Å)