4YDV

STRUCTURE OF THE ANTIBODY 7B2 THAT CAPTURES HIV-1 VIRIONS

4YDV の概要

• エントリーDOI: 10.2210/pdb4ydv/pdb
• 分子名称: HIV GP41 PEPTIDE GP41(596-606), HIV ANTIBODY 7B2 LIGHT CHAIN,Ig kappa chain C region, HIV ANTIBODY 7B2 HEAVY CHAIN,IgG H chain, ... (4 entities in total)
• 機能のキーワード: igg, hiv, antibody, hiv gp41 envelope protein, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 115163.25

構造登録者

Nicely, N.I.,Pemble IV, C.W. (登録日: 2015-02-23, 公開日: 2015-08-12, 最終更新日: 2021-03-24)

• 主引用文献: Santra, S.,Tomaras, G.D.,Warrier, R.,Nicely, N.I.,Liao, H.X.,Pollara, J.,Liu, P.,Alam, S.M.,Zhang, R.,Cocklin, S.L.,Shen, X.,Duffy, R.,Xia, S.M.,Schutte, R.J.,Pemble Iv, C.W.,Dennison, S.M.,Li, H.,Chao, A.,Vidnovic, K.,Evans, A.,Klein, K.,Kumar, A.,Robinson, J.,Landucci, G.,Forthal, D.N.,Montefiori, D.C.,Kaewkungwal, J.,Nitayaphan, S.,Pitisuttithum, P.,Rerks-Ngarm, S.,Robb, M.L.,Michael, N.L.,Kim, J.H.,Soderberg, K.A.,Giorgi, E.E.,Blair, L.,Korber, B.T.,Moog, C.,Shattock, R.J.,Letvin, N.L.,Schmitz, J.E.,Moody, M.A.,Gao, F.,Ferrari, G.,Shaw, G.M.,Haynes, B.F.; Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.; Plos Pathog., 11:e1005042-e1005042, 2015; PubMed: 26237403; DOI: 10.1371/journal.ppat.1005042

実験手法

X-RAY DIFFRACTION (2.7 Å)