4YC0

Crystal structure of ADP-ribosyltransferase Vis in complex with M6 Inhibitor

4YC0 の概要

• エントリーDOI: 10.2210/pdb4yc0/pdb
• 分子名称: Putative NAD(+)--arginine ADP-ribosyltransferase Vis, 2-(4-oxidanylidene-3~{H}-phthalazin-1-yl)ethanoic acid (3 entities in total)
• 機能のキーワード: inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Vibrio splendidus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27241.23

構造登録者

Ravulapalli, R.,Merrill, A.R. (登録日: 2015-02-19, 公開日: 2015-11-18, 最終更新日: 2023-09-27)

• 主引用文献: Ravulapalli, R.,Lugo, M.R.,Pfoh, R.,Visschedyk, D.,Poole, A.,Fieldhouse, R.J.,Pai, E.F.,Merrill, A.R.; Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus.; Biochemistry, 54:5920-5936, 2015; PubMed: 26352925; DOI: 10.1021/acs.biochem.5b00921

実験手法

X-RAY DIFFRACTION (1.5 Å)