4Y8N
Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAE-ep
Summary for 4Y8N
Entry DOI | 10.2210/pdb4y8n/pdb |
Related | 1RYP |
Descriptor | Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (18 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, proteasome, mutant, inhibitor, binding analysis, hydrolase/hydrolase inhibitor |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Cellular location | Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451 |
Total number of polymer chains | 30 |
Total formula weight | 730497.57 |
Authors | Huber, E.M.,Groll, M. (deposition date: 2015-02-16, release date: 2015-06-17, Last modification date: 2024-01-10) |
Primary citation | Huber, E.M.,de Bruin, G.,Heinemeyer, W.,Paniagua Soriano, G.,Overkleeft, H.S.,Groll, M. Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137:7835-7842, 2015 Cited by PubMed: 26020686DOI: 10.1021/jacs.5b03688 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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