4Y62

AAGlyB in complex with amino-acid analogues

4Y62 の概要

• エントリーDOI: 10.2210/pdb4y62/pdb
• 分子名称: Histo-blood group ABO system transferase, octyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside, 5'-deoxy-5'-{[(2R)-3-hydroxy-2-(4-phenyl-1H-1,2,3-triazol-1-yl)propanoyl]amino}uridine, ... (4 entities in total)
• 機能のキーワード: aaglyb, inhibitor, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41843.63

構造登録者

Wang, S.,Cuesta-Seijo, J.A.,Striebeck, A.,Lafont, D.,Palcic, M.M.,Vidal, S. (登録日: 2015-02-12, 公開日: 2015-09-16, 最終更新日: 2024-01-10)

• 主引用文献: Wang, S.,Cuesta-Seijo, J.A.,Striebeck, A.,Lafont, D.,Palcic, M.M.,Vidal, S.; Design of Glycosyltransferase Inhibitors: Serine Analogues as Pyrophosphate Surrogates?; Chempluschem, 80:1525-1532, 2015; DOI: 10.1002/cplu.201500282

実験手法

X-RAY DIFFRACTION (1.6 Å)