4Y4L

Crystal structure of yeast Thi4-C205S

Summary for 4Y4L

• Entry DOI: 10.2210/pdb4y4l/pdb
• Descriptor: Thiamine thiazole synthase, (2E)-2-[(2S,4R)-5-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-3-oxidanylidene-pentan-2-yl]iminoethanoic acid (3 entities in total)
• Functional Keywords: biosynthetic protein
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• Cellular location: Cytoplasm: P32318
• Total number of polymer chains: 4
• Total formula weight: 151134.13

Authors

Zhang, X.,Ealick, S.E. (deposition date: 2015-02-10, release date: 2016-03-09, Last modification date: 2023-09-27)

• Primary citation: Zhang, X.,Eser, B.E.,Chanani, P.K.,Begley, T.P.,Ealick, S.E.; Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases.; Biochemistry, 55:1826-1838, 2016; PubMed: 26919468; DOI: 10.1021/acs.biochem.6b00030

Experimental method

X-RAY DIFFRACTION (2 Å)