4Y34
Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143
Summary for 4Y34
Entry DOI | 10.2210/pdb4y34/pdb |
Descriptor | 3D polymerase, 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), SULFATE ION, ... (5 entities in total) |
Functional Keywords | polymerase, picornavirus, coxsackievirus, gpc-n143, inhibitor, transferase, viral protein |
Biological source | Coxsackievirus B3 More |
Total number of polymer chains | 1 |
Total formula weight | 54436.77 |
Authors | Vives-Adrian, L.,Ferrer-Orta, C.,Cerdaguer, N. (deposition date: 2015-02-10, release date: 2015-04-01, Last modification date: 2024-01-10) |
Primary citation | van der Linden, L.,Vives-Adrian, L.,Selisko, B.,Ferrer-Orta, C.,Liu, X.,Lanke, K.,Ulferts, R.,De Palma, A.M.,Tanchis, F.,Goris, N.,Lefebvre, D.,De Clercq, K.,Leyssen, P.,Lacroix, C.,Purstinger, G.,Coutard, B.,Canard, B.,Boehr, D.D.,Arnold, J.J.,Cameron, C.E.,Verdaguer, N.,Neyts, J.,van Kuppeveld, F.J. The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11:e1004733-e1004733, 2015 Cited by PubMed: 25799064DOI: 10.1371/journal.ppat.1004733 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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