4Y34

Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143

4Y34 の概要

• エントリーDOI: 10.2210/pdb4y34/pdb
• 分子名称: 3D polymerase, 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), SULFATE ION, ... (5 entities in total)
• 機能のキーワード: polymerase, picornavirus, coxsackievirus, gpc-n143, inhibitor, transferase, viral protein
• 由来する生物種: Coxsackievirus B3; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54436.77

構造登録者

Vives-Adrian, L.,Ferrer-Orta, C.,Cerdaguer, N. (登録日: 2015-02-10, 公開日: 2015-04-01, 最終更新日: 2024-01-10)

• 主引用文献: van der Linden, L.,Vives-Adrian, L.,Selisko, B.,Ferrer-Orta, C.,Liu, X.,Lanke, K.,Ulferts, R.,De Palma, A.M.,Tanchis, F.,Goris, N.,Lefebvre, D.,De Clercq, K.,Leyssen, P.,Lacroix, C.,Purstinger, G.,Coutard, B.,Canard, B.,Boehr, D.D.,Arnold, J.J.,Cameron, C.E.,Verdaguer, N.,Neyts, J.,van Kuppeveld, F.J.; The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.; Plos Pathog., 11:e1004733-e1004733, 2015; PubMed: 25799064; DOI: 10.1371/journal.ppat.1004733

実験手法

X-RAY DIFFRACTION (2.7 Å)