4Y24

Complex of human Galectin-1 and TD-139

4Y24 の概要

関連するPDBエントリー4Y1V 4Y1Z 4Y1Y 4Y1U 4Y1X 4Y22 4Y20
分子名称Galectin-1, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside (3 entities in total)
機能のキーワードcomplex, galectin-1, tdg, td-139, sugar binding protein
由来する生物種Homo sapiens (Human)
細胞内の位置Secreted, extracellular space, extracellular matrix  P09382
ポリマー鎖数2
分子量合計34959.2
構造登録者
Lin, H.Y.,Hsieh, T.J.,Lin, C.H. (登録日: 2015-02-09, 公開日: 2016-04-27, 最終更新日: 2016-08-03)
主引用文献
Hsieh, T.J.,Lin, H.Y.,Tu, Z.,Lin, T.C.,Wu, S.C.,Tseng, Y.Y.,Liu, F.T.,Hsu, S.T.,Lin, C.H.
Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors.
Sci Rep, 6:29457-29457, 2016
PubMed: 27416897 (主引用文献が同じPDBエントリー)
DOI: 10.1038/srep29457
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.32 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.250500.9%6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード