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4Y20

Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc

Summary for 4Y20
Entry DOI10.2210/pdb4y20/pdb
Related4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y22 4Y24 4Y26
Related PRD IDPRD_900025
DescriptorGalectin-1, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total)
Functional Keywordscomplex, galectin-1, lectin, neuacalpha2-3galbeta1-4glc, sugar binding protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight35073.04
Authors
Lin, H.Y.,Hsieh, T.J.,Lin, C.H. (deposition date: 2015-02-09, release date: 2016-04-06, Last modification date: 2020-07-29)
Primary citationLin, H.Y.,Hsieh, T.J.,Tu, Z.,Huang, B.S.,Wu, S.C.,Chien, C.T.,Hsu, S.T.,Lin, C.H.
Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.204 Å)
Structure validation

217705

건을2024-03-27부터공개중

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