4Y0Y
Trypsin in complex with with BPTI
Summary for 4Y0Y
Entry DOI | 10.2210/pdb4y0y/pdb |
Related | 4Y0Z 4Y10 4Y11 |
Descriptor | Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ... (6 entities in total) |
Functional Keywords | hydrolase inhibitors, metal-binding, serine protease, hydrolase-inhibitor complex, hydrolase\inhibitor |
Biological source | Bos taurus (cattle) More |
Cellular location | Secreted, extracellular space: P00760 Secreted: P00974 |
Total number of polymer chains | 2 |
Total formula weight | 30940.69 |
Authors | Loll, B.,Ye, S.,Berger, A.A.,Muelow, U.,Alings, C.,Wahl, M.C.,Koksch, B. (deposition date: 2015-02-06, release date: 2015-06-24, Last modification date: 2024-01-10) |
Primary citation | Ye, S.,Loll, B.,Berger, A.A.,Mulow, U.,Alings, C.,Wahl, M.C.,Koksch, B. Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6:5246-5254, 2015 Cited by PubMed: 29449928DOI: 10.1039/c4sc03227f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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