4Y0J
H/D exchanged human carbonic anhydrase II pH 6 room temperature neutron crystal structure.
Summary for 4Y0J
Entry DOI | 10.2210/pdb4y0j/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION (3 entities in total) |
Functional Keywords | neutron, proton transfer, h/d exchanged, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29136.19 |
Authors | Fisher, S.Z. (deposition date: 2015-02-06, release date: 2015-04-22, Last modification date: 2024-01-10) |
Primary citation | Michalczyk, R.,Unkefer, C.J.,Bacik, J.P.,Schrader, T.E.,Ostermann, A.,Kovalevsky, A.Y.,McKenna, R.,Fisher, S.Z. Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer. Proc.Natl.Acad.Sci.USA, 112:5673-5678, 2015 Cited by PubMed: 25902526DOI: 10.1073/pnas.1502255112 PDB entries with the same primary citation |
Experimental method | NEUTRON DIFFRACTION (2 Å) |
Structure validation
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