4XWX

Crystal structure of the PTB domain of SHC

Summary for 4XWX

• Entry DOI: 10.2210/pdb4xwx/pdb
• Descriptor: SHC-transforming protein 1, 1,2-ETHANEDIOL, SODIUM ION, ... (4 entities in total)
• Functional Keywords: signaling protein, phosphotyrosine binding domain, signal transduction, structural genomics consortium (sgc)
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm. Isoform p46Shc: Mitochondrion matrix . Isoform p66Shc: Mitochondrion : P29353
• Total number of polymer chains: 1
• Total formula weight: 18529.31

Authors

Chaikuad, A.,Tallant, C.,Krojer, T.,Dixon-Clarke, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2015-01-29, release date: 2015-02-25)

• Primary citation: Chaikuad, A.,Tallant, C.,Krojer, T.,Dixon-Clarke, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of the PTB domain of SHC; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.87 Å)