4XVJ
STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC 2 REGION 412-423 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY HC33.1
Summary for 4XVJ
Entry DOI | 10.2210/pdb4xvj/pdb |
Descriptor | HCV E2 antigen, antibody heavy chain variable domain, antibody light chain variable domain, ... (4 entities in total) |
Functional Keywords | antibody-antigen complex, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 28246.96 |
Authors | Li, Y.,Mariuzza, R.A. (deposition date: 2015-01-27, release date: 2015-03-11, Last modification date: 2016-12-28) |
Primary citation | Li, Y.,Pierce, B.G.,Wang, Q.,Keck, Z.Y.,Fuerst, T.R.,Foung, S.K.,Mariuzza, R.A. Structural basis for penetration of the glycan shield of hepatitis C virus e2 glycoprotein by a broadly neutralizing human antibody. J.Biol.Chem., 290:10117-10125, 2015 Cited by PubMed: 25737449DOI: 10.1074/jbc.M115.643528 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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