4XRQ

Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I) in complex with PF-3450074

Summary for 4XRQ

Entry DOI	10.2210/pdb4xrq/pdb
Related	4XRO
Descriptor	Capsid protein p24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE (3 entities in total)
Functional Keywords	viral protein, capsid, inhibitor
Biological source	Human immunodeficiency virus 1 (HIV-1)
Total number of polymer chains	1
Total formula weight	25894.84
Authors	Price, A.J.,James, L.C. (deposition date: 2015-01-21, release date: 2015-07-15, Last modification date: 2024-01-10)
Primary citation	Zhou, J.,Price, A.J.,Halambage, U.D.,James, L.C.,Aiken, C. HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry. J.Virol., 89:9068-9079, 2015 Cited by PubMed: 26109731 DOI: 10.1128/JVI.00340-15 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation