4XRA

Salmonella typhimurium AhpC T43S mutant

4XRA の概要

• エントリーDOI: 10.2210/pdb4xra/pdb
• 関連するPDBエントリー: 1YEP 4MA9 4XRD
• 分子名称: Alkyl hydroperoxide reductase subunit C, CHLORIDE ION, POTASSIUM ION, ... (5 entities in total)
• 機能のキーワード: peroxiredoxin, ff, prxi, conformation, oxidoreductase
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 103668.24

構造登録者

Perkins, A.,Brereton, A.E.,Nelson, K.,Parsonage, D.,Poole, L.,Karplus, P.A. (登録日: 2015-01-20, 公開日: 2016-01-20, 最終更新日: 2023-09-27)

主引用文献

Nelson, K.J.,Perkins, A.,Van Swearingen, A.E.D.,Hartman, S.,Brereton, A.E.,Parsonage, D.,Salsbury Jr., F.R.,Karplus, P.A.,Poole, L.B.
Experimentally Dissecting the Origins of Peroxiredoxin Catalysis.
Antioxid.Redox Signal., 28:521-536, 2018

PubMed Abstract: Peroxiredoxins (Prxs) are ubiquitous cysteine-based peroxidases involved in oxidant defense and signal transduction. Despite much study, the precise roles of conserved residues remain poorly defined. In this study, we carried out extensive functional and structural characterization of 10 variants of such residues in a model decameric bacterial Prx.

PubMed: 28375740
DOI: 10.1089/ars.2016.6922

実験手法

X-RAY DIFFRACTION (1.75 Å)