4XLI

Crystal structure of Abl2/Arg kinase in complex with dasatinib

4XLI の概要

• エントリーDOI: 10.2210/pdb4xli/pdb
• 分子名称: Non-specific protein-tyrosine kinase, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, ZINC ION, ... (4 entities in total)
• 機能のキーワード: transferase, inhibitor, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 62580.09

構造登録者

Ha, B.H.,Boggon, T.J. (登録日: 2015-01-13, 公開日: 2015-04-01, 最終更新日: 2023-09-27)

• 主引用文献: Ha, B.H.,Simpson, M.A.,Koleske, A.J.,Boggon, T.J.; Structure of the ABL2/ARG kinase in complex with dasatinib.; Acta Crystallogr.,Sect.F, 71:443-448, 2015; PubMed: 25849507; DOI: 10.1107/S2053230X15004793

実験手法

X-RAY DIFFRACTION (2.5 Å)