4XHU
The complex structure of Timeless_PAB and PARP-1_catalytic domain
Summary for 4XHU
Entry DOI | 10.2210/pdb4xhu/pdb |
Related | 4XHT 4XHW |
Descriptor | Poly [ADP-ribose] polymerase 1, Protein timeless homolog, GLYCEROL, ... (6 entities in total) |
Functional Keywords | dna damage response, transferase-replication complex, transferase/replication |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P09874 Q9UNS1 |
Total number of polymer chains | 4 |
Total formula weight | 103896.36 |
Authors | |
Primary citation | Xie, S.,Mortusewicz, O.,Ma, H.T.,Herr, P.,Poon, R.R.,Helleday, T.,Qian, C. Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair. Mol.Cell, 60:163-176, 2015 Cited by PubMed: 26344098DOI: 10.1016/j.molcel.2015.07.031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.089 Å) |
Structure validation
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