4XHE

Crystal Structure of A-AChBP in complex with pinnatoxin A

Summary for 4XHE

• Entry DOI: 10.2210/pdb4xhe/pdb
• Descriptor: Soluble acetylcholine receptor, Pinnatoxin A, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: receptor, phycotoxin, pinnatoxin, membrane protein, acetylcholine-binding protein
• Biological source: Aplysia californica (California sea hare)
• Total number of polymer chains: 10
• Total formula weight: 254585.22

Authors

Bourne, Y.,Sulzenbacher, G.,Marchot, P. (deposition date: 2015-01-05, release date: 2015-06-03, Last modification date: 2024-01-10)

• Primary citation: Bourne, Y.,Sulzenbacher, G.,Radic, Z.,Araoz, R.,Reynaud, M.,Benoit, E.,Zakarian, A.,Servent, D.,Molgo, J.,Taylor, P.,Marchot, P.; Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha 7 from Muscle alpha 12 beta gamma delta nAChRs.; Structure, 23:1106-1115, 2015; PubMed: 26004441; DOI: 10.1016/j.str.2015.04.009

Experimental method

X-RAY DIFFRACTION (1.9 Å)