4X9R
PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 3B
Summary for 4X9R
| Entry DOI | 10.2210/pdb4x9r/pdb |
| Related | 4X9V 4X9W 4o6w |
| Descriptor | Serine/threonine-protein kinase PLK1, Phosphopeptide macrocycle 3B (3 entities in total) |
| Functional Keywords | polo box domain phosphopeptide macrocycle inhibitor complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 28247.26 |
| Authors | Grant, R.A.,Qian, W.-J.,Yaffe, M.B.,Burke, T.R. (deposition date: 2014-12-11, release date: 2015-07-29, Last modification date: 2023-11-15) |
| Primary citation | Qian, W.J.,Park, J.E.,Grant, R.,Lai, C.C.,Kelley, J.A.,Yaffe, M.B.,Lee, K.S.,Burke, T.R. Neighbor-directed histidine N ( tau )-alkylation: A route to imidazolium-containing phosphopeptide macrocycles. Biopolymers, 104:663-673, 2015 Cited by PubMed: 26152807DOI: 10.1002/bip.22698 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.398 Å) |
Structure validation
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