4X6Q
An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
Summary for 4X6Q
Entry DOI | 10.2210/pdb4x6q/pdb |
Related | 4X6R |
Descriptor | cAMP-dependent protein kinase type II-beta regulatory subunit, cAMP-dependent protein kinase catalytic subunit alpha (3 entities in total) |
Functional Keywords | pka, membrane binding, molecular switch, transferase |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 86931.27 |
Authors | Zhang, P.,Ye, F.,Bastidas, A.C.,Kornev, A.P.,Ginsberg, M.H.,Taylor, S.S. (deposition date: 2014-12-08, release date: 2015-07-22, Last modification date: 2019-12-25) |
Primary citation | Zhang, P.,Ye, F.,Bastidas, A.C.,Kornev, A.P.,Wu, J.,Ginsberg, M.H.,Taylor, S.S. An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes. Structure, 23:1563-1572, 2015 Cited by PubMed: 26278174DOI: 10.1016/j.str.2015.07.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
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