4X56
Structure of the class D Beta-Lactamase OXA-160 V130D in Acyl-Enzyme Complex with Ceftazidime
Summary for 4X56
Entry DOI | 10.2210/pdb4x56/pdb |
Related | 4X53 4X55 |
Descriptor | Class D beta-lactamase OXA-160, ACYLATED CEFTAZIDIME (3 entities in total) |
Functional Keywords | hydrolase, carbapenemase, antibiotic |
Biological source | Acinetobacter baumannii |
Total number of polymer chains | 1 |
Total formula weight | 28150.26 |
Authors | Clasman, J.R.,June, C.M.,Powers, R.A.,Leonard, D.A. (deposition date: 2014-12-04, release date: 2015-03-11, Last modification date: 2023-09-27) |
Primary citation | Mitchell, J.M.,Clasman, J.R.,June, C.M.,Kaitany, K.C.,LaFleur, J.R.,Taracila, M.A.,Klinger, N.V.,Bonomo, R.A.,Wymore, T.,Szarecka, A.,Powers, R.A.,Leonard, D.A. Structural Basis of Activity against Aztreonam and Extended Spectrum Cephalosporins for Two Carbapenem-Hydrolyzing Class D beta-Lactamases from Acinetobacter baumannii. Biochemistry, 54:1976-1987, 2015 Cited by PubMed: 25710192DOI: 10.1021/bi501547k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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