4X4M
Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high affinity IgG binding
Summary for 4X4M
Entry DOI | 10.2210/pdb4x4m/pdb |
Descriptor | Ig gamma-1 chain C region, High affinity immunoglobulin gamma Fc receptor I, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 167346.95 |
Authors | |
Primary citation | Lu, J.,Chu, J.,Zou, Z.,Hamacher, N.B.,Rixon, M.W.,Sun, P.D. Structure of Fc gamma RI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding. Proc.Natl.Acad.Sci.USA, 112:833-838, 2015 Cited by PubMed: 25561553DOI: 10.1073/pnas.1418812112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.485 Å) |
Structure validation
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