4X4M

Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high affinity IgG binding

4X4M の概要

• エントリーDOI: 10.2210/pdb4x4m/pdb
• 分子名称: Ig gamma-1 chain C region, High affinity immunoglobulin gamma Fc receptor I, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 167346.95

構造登録者

Lu, J.,Sun, P.D. (登録日: 2014-12-03, 公開日: 2015-04-08, 最終更新日: 2020-07-29)

• 主引用文献: Lu, J.,Chu, J.,Zou, Z.,Hamacher, N.B.,Rixon, M.W.,Sun, P.D.; Structure of Fc gamma RI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding.; Proc.Natl.Acad.Sci.USA, 112:833-838, 2015; PubMed: 25561553; DOI: 10.1073/pnas.1418812112

実験手法

X-RAY DIFFRACTION (3.485 Å)