4X47

Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with Neu5Ac2en

4X47 の概要

• エントリーDOI: 10.2210/pdb4x47/pdb
• 分子名称: Anhydrosialidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: intramolecular, trans-sialidase, sialidase, neuraminidase, neu5ac2en, dana, inhibitor, complex, hydrolase, anhydrosialidase
• 由来する生物種: Ruminococcus gnavus ATCC 29149
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54378.83

構造登録者

Owen, C.D.,Tailford, L.E.,Taylor, G.L.,Juge, N. (登録日: 2014-12-02, 公開日: 2015-07-22, 最終更新日: 2024-01-10)

• 主引用文献: Tailford, L.E.,Owen, C.D.,Walshaw, J.,Crost, E.H.,Hardy-Goddard, J.,Le Gall, G.,de Vos, W.M.,Taylor, G.L.,Juge, N.; Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation.; Nat Commun, 6:7624-7624, 2015; PubMed: 26154892; DOI: 10.1038/ncomms8624

実験手法

X-RAY DIFFRACTION (2 Å)