4X2Z

Structural view and substrate specificity of papain-like protease from Avian Infectious Bronchitis Virus

4X2Z の概要

• エントリーDOI: 10.2210/pdb4x2z/pdb
• 分子名称: Nonstructural protein 3, ZINC ION (3 entities in total)
• 機能のキーワード: plpro, de-ubiquitination, ibv, coronavirus, hydrolase
• 由来する生物種: Avian infectious bronchitis virus (IBV)
• 細胞内の位置: Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6Y1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36119.06

構造登録者

Kong, L.,Shaw, N.,Yan, L.,Lou, Z.,Rao, Z. (登録日: 2014-11-27, 公開日: 2015-01-28, 最終更新日: 2015-04-01)

• 主引用文献: Kong, L.,Shaw, N.,Yan, L.,Lou, Z.,Rao, Z.; Structural View and Substrate Specificity of Papain-like Protease from Avian Infectious Bronchitis Virus.; J.Biol.Chem., 290:7160-7168, 2015; PubMed: 25609249; DOI: 10.1074/jbc.M114.628636

実験手法

X-RAY DIFFRACTION (2.15 Å)