4WV3
Crystal structure of the anthranilate CoA ligase AuaEII in complex with anthranoyl-AMP
Summary for 4WV3
Entry DOI | 10.2210/pdb4wv3/pdb |
Descriptor | Anthranilate-CoA ligase, 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine (3 entities in total) |
Functional Keywords | anthranilate, coa ligase, aurachin, natural product biosynthesis, ligase-ligase inhibitor complex, ligase/ligase inhibitor |
Biological source | Stigmatella aurantiaca |
Total number of polymer chains | 2 |
Total formula weight | 118284.35 |
Authors | Tsai, S.C.,Muller, R.,Jackson, D.R.,Tu, S.S.,Nguyen, M.,Barajas, J.F.,Pistorious, D.,Krug, D. (deposition date: 2014-11-04, release date: 2015-11-11, Last modification date: 2023-09-27) |
Primary citation | Jackson, D.R.,Tu, S.S.,Nguyen, M.,Barajas, J.F.,Schaub, A.J.,Krug, D.,Pistorius, D.,Luo, R.,Muller, R.,Tsai, S.C. Structural Insights into Anthranilate Priming during Type II Polyketide Biosynthesis. Acs Chem.Biol., 11:95-103, 2016 Cited by PubMed: 26473393DOI: 10.1021/acschembio.5b00500 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.599 Å) |
Structure validation
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