4WUX

Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D) Complexed with Mannose

Summary for 4WUX

• Entry DOI: 10.2210/pdb4wux/pdb
• Related: 4WUW
• Descriptor: Pulmonary surfactant-associated protein A, alpha-D-mannopyranose, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: collectin, carbohydrate binding, lectin, lipid binding, sugar binding protein
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 1
• Total formula weight: 17345.08

Authors

Rynkiewicz, M.J.,Wu, H.,Cafarella, T.R.,Nikolaidis, N.M.,Head, J.F.,Seaton, B.A.,McCormack, F.X. (deposition date: 2014-11-03, release date: 2016-02-10, Last modification date: 2023-09-27)

• Primary citation: Rynkiewicz, M.J.,Wu, H.,Cafarella, T.R.,Nikolaidis, N.M.,Head, J.F.,Seaton, B.A.,McCormack, F.X.; Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop; To be published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)