4WSK

Crystal structure of a bacterial fucosidase with phenyl((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)methanone

4WSK の概要

• エントリーDOI: 10.2210/pdb4wsk/pdb
• 分子名称: Alpha-L-fucosidase, SULFATE ION, N-[(1S,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methylcyclohexyl]benzamide, ... (5 entities in total)
• 機能のキーワード: fucosidase complex covalent inhibitor, hydrolase
• 由来する生物種: Bacteroides thetaiotaomicron
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 218165.34

構造登録者

Davies, G.J. (登録日: 2014-10-28, 公開日: 2014-11-12, 最終更新日: 2024-01-10)

• 主引用文献: Jiang, J.,Kallemeijn, W.W.,Wright, D.W.,van den Nieuwendijk, A.M.C.H.,Rohde, V.C.,Folch, E.C.,van den Elst, H.,Florea, B.I.,Scheij, S.,Donker-Koopman, W.E.,Verhoek, M.,Li, N.,Schurmann, M.,Mink, D.,Boot, R.G.,Codee, J.D.C.,van der Marel, G.A.,Davies, G.J.,Aerts, J.M.F.G.,Overkleeft, H.S.; In vitroandin vivocomparative and competitive activity-based protein profiling of GH29 alpha-l-fucosidases.; Chem Sci, 6:2782-false, 2015; PubMed: 29142681; DOI: 10.1039/c4sc03739a

実験手法

X-RAY DIFFRACTION (1.92 Å)