4WKM

AmpR effector binding domain from Citrobacter freundii bound to UDP-MurNAc-pentapeptide

Summary for 4WKM

• Entry DOI: 10.2210/pdb4wkm/pdb
• Related: 3kos 3kot
• Descriptor: LysR family transcriptional regulator, ALA-FGA-API-DAL-DAL, GLYCEROL, ... (5 entities in total)
• Functional Keywords: lysr-type transcriptional regulator, lttr, udp-murnac-pentapeptide, transcription
• Biological source: Citrobacter freundii ATCC 8090 = MTCC 1658; More
• Total number of polymer chains: 16
• Total formula weight: 204709.12

Authors

Vadlamani, G.,Reeve, T.M.,Mark, B.L. (deposition date: 2014-10-02, release date: 2014-12-17, Last modification date: 2023-11-15)

• Primary citation: Vadlamani, G.,Thomas, M.D.,Patel, T.R.,Donald, L.J.,Reeve, T.M.,Stetefeld, J.,Standing, K.G.,Vocadlo, D.J.,Mark, B.L.; The beta-Lactamase Gene Regulator AmpR Is a Tetramer That Recognizes and Binds the d-Ala-d-Ala Motif of Its Repressor UDP-N-acetylmuramic Acid (MurNAc)-pentapeptide.; J.Biol.Chem., 290:2630-2643, 2015; PubMed: 25480792; DOI: 10.1074/jbc.M114.618199

Experimental method

X-RAY DIFFRACTION (2.15 Å)