4WJL

Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels

4WJL の概要

• エントリーDOI: 10.2210/pdb4wjl/pdb
• 分子名称: Inactive dipeptidyl peptidase 10, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: inactive dipeptidyl peptidase 10, dpp4 structure homologue, alpha/beta hydrolase, beta-propeller, membrane protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cell membrane ; Single-pass type II membrane protein : Q8N608
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 168725.84

構造登録者

Bezerra, G.A.,Dobrovetsky, E.,Seitova, A.,Fedosyuk, S.,Dhe-Paganon, S.,Gruber, K. (登録日: 2014-09-30, 公開日: 2015-03-18, 最終更新日: 2024-01-10)

• 主引用文献: Bezerra, G.A.,Dobrovetsky, E.,Seitova, A.,Fedosyuk, S.,Dhe-Paganon, S.,Gruber, K.; Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels.; Sci Rep, 5:8769-8769, 2015; PubMed: 25740212; DOI: 10.1038/srep08769

実験手法

X-RAY DIFFRACTION (3.4 Å)