4WHU
BROMO domain of CREB binding protein
Summary for 4WHU
Entry DOI | 10.2210/pdb4whu/pdb |
Descriptor | CREB-binding protein, 2-methoxy-4-{1-[2-(morpholin-4-yl)ethyl]-2-(2-phenylethyl)-1H-benzimidazol-5-yl}cyclohepta-2,4,6-trien-1-one (3 entities in total) |
Functional Keywords | bromo domain, creb binding protein, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q92793 |
Total number of polymer chains | 1 |
Total formula weight | 14692.92 |
Authors | |
Primary citation | Hett, E.C.,Piatnitski Chekler, E.L.,Basak, A.,Bonin, P.D.,Denny, R.A.,Flick, A.C.,Geoghegan, K.F.,Liu, S.,Pletcher, M.T.,Robinson, R.P.,Sahasrabudhe, P.,Salter, S.,Stock, I.A.,Jones, L.H. Direct photocapture of bromodomains using tropolone chemical probes To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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