4WEU

Co-complex structure of the F4 fimbrial adhesin FaeG variant ad with llama single domain antibody V3

Summary for 4WEU

• Entry DOI: 10.2210/pdb4weu/pdb
• Related: 3HLR
• Descriptor: Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AD (3 entities in total)
• Functional Keywords: complex, adhesin, nanobody, llama single domain antibody, cell adhesion
• Biological source: Lama glama (Llama); More
• Cellular location: Fimbrium: P14191
• Total number of polymer chains: 4
• Total formula weight: 86520.01

Authors

Moonens, K.,Van den Broeck, I.,Pardon, E.,De Kerpel, M.,Remaut, H.,De Greve, H. (deposition date: 2014-09-11, release date: 2015-02-04, Last modification date: 2024-01-10)

• Primary citation: Moonens, K.,Van den Broeck, I.,Okello, E.,Pardon, E.,De Kerpel, M.,Remaut, H.,De Greve, H.; Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.; Vet. Res., 46:14-14, 2015; PubMed: 25828907; DOI: 10.1186/s13567-015-0151-x

Experimental method

X-RAY DIFFRACTION (2.61 Å)