4WA4

The crystal structure of neuraminidase from a H3N8 influenza virus isolated from New England harbor seals in complex with oseltamivir carboxylate

4WA4 の概要

• エントリーDOI: 10.2210/pdb4wa4/pdb
• 関連するPDBエントリー: 4WA1 4WA2 4WA3 4WA5
• 分子名称: Neuraminidase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, ... (5 entities in total)
• 機能のキーワード: neuraminidase, influenza virus, seal, viral protein-inhibitor complex, viral protein/inhibitor
• 由来する生物種: Influenza A virus (A/harbor seal/Massachusetts/1/2011(H3N8))
• 細胞内の位置: Virion membrane : I6NW33
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43628.11

構造登録者

Yang, H.,Villanueva, J.M.,Gubareva, L.V.,Stevens, J. (登録日: 2014-08-28, 公開日: 2015-01-14, 最終更新日: 2023-12-27)

• 主引用文献: Yang, H.,Nguyen, H.T.,Carney, P.J.,Guo, Z.,Chang, J.C.,Jones, J.,Davis, C.T.,Villanueva, J.M.,Gubareva, L.V.,Stevens, J.; Structural and Functional Analysis of Surface Proteins from an A(H3N8) Influenza Virus Isolated from New England Harbor Seals.; J.Virol., 89:2801-2812, 2015; PubMed: 25540377; DOI: 10.1128/JVI.02723-14

実験手法

X-RAY DIFFRACTION (1.95 Å)