4W9X
Crystal Structure of BMP-2-inducible kinase in complex with baricitinib
Summary for 4W9X
Entry DOI | 10.2210/pdb4w9x/pdb |
Related | 4W9W |
Descriptor | BMP-2-inducible protein kinase, 1,2-ETHANEDIOL, Baricitinib, ... (4 entities in total) |
Functional Keywords | kinase, small-molecule, catalytic domain, protein binding, inhibitor, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9NSY1 |
Total number of polymer chains | 1 |
Total formula weight | 35286.59 |
Authors | Sorrell, F.J.,Elkins, J.M.,Krojer, T.,Williams, E.,Savitsky, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2014-08-28, release date: 2014-09-10, Last modification date: 2024-05-08) |
Primary citation | Sorrell, F.J.,Szklarz, M.,Abdul Azeez, K.R.,Elkins, J.M.,Knapp, S. Family-wide Structural Analysis of Human Numb-Associated Protein Kinases. Structure, 24:401-411, 2016 Cited by PubMed: 26853940DOI: 10.1016/j.str.2015.12.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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