4W8P

Crystal structure of RIAM TBS1 in complex with talin R7R8 domains

4W8P の概要

• エントリーDOI: 10.2210/pdb4w8p/pdb
• 分子名称: Talin-1, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: talin, rod domains, r7r8, r8, riam, tbs1, peptide binding protein
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side : P26039; Cell membrane ; Peripheral membrane protein : Q8R5A3
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34128.39

構造登録者

Chang, Y.C.E.,Zhang, H.,Wu, J. (登録日: 2014-08-25, 公開日: 2014-12-03, 最終更新日: 2023-09-27)

• 主引用文献: Chang, Y.C.,Zhang, H.,Franco-Barraza, J.,Brennan, M.L.,Patel, T.,Cukierman, E.,Wu, J.; Structural and Mechanistic Insights into the Recruitment of Talin by RIAM in Integrin Signaling.; Structure, 22:1810-1820, 2014; PubMed: 25465129; DOI: 10.1016/j.str.2014.09.020

実験手法

X-RAY DIFFRACTION (1.5 Å)