4W7Z

Tetrameric BAP29 vDED without disulfide bonds

4W7Z の概要

• エントリーDOI: 10.2210/pdb4w7z/pdb
• 関連するPDBエントリー: 4W7Y
• 分子名称: B-cell receptor-associated protein 29, SULFATE ION, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: coiled coil, nanomaterial, transport protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q9UHQ4
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 31770.09

構造登録者

Quistgaard, E.M. (登録日: 2014-08-22, 公開日: 2014-10-29, 最終更新日: 2024-05-01)

主引用文献

Quistgaard, E.M.
A disulfide polymerized protein crystal.
Chem.Commun.(Camb.), 50:14995-14997, 2014

PubMed Abstract: The vDED coiled coil domain from human BAP29 was crystallized in dimeric and tetrameric forms. For the dimer, a disulfide bond was unexpectedly found to bridge a crystal contact, resulting in complete cross-linking along the c-axis. This indicates that it is in principle possible to design spontaneously polymerizing protein crystals.

PubMed: 25327138
DOI: 10.1039/c4cc07326f

実験手法

X-RAY DIFFRACTION (2.2 Å)