4W29

70S ribosome translocation intermediate containing elongation factor EFG/GDP/fusidic acid, mRNA, and tRNAs trapped in the AP/AP pe/E chimeric hybrid state.

This is a non-PDB format compatible entry.

Summary for 4W29

• Entry DOI: 10.2210/pdb4w29/pdb
• Descriptor: 30S ribosomal protein S2, 30S ribosomal protein S11, 30S ribosomal protein S12, ... (64 entities in total)
• Functional Keywords: chimeric hybrid state ribosome, translocation intermediate, ef-g, mrna, trna, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039); More
• Cellular location: Cytoplasm : Q72I01
• Total number of polymer chains: 122
• Total formula weight: 4630819.49

Authors

Zhou, J.,Lancaster, L.,Donohue, J.P.,Noller, H.F. (deposition date: 2014-07-02, release date: 2014-10-01, Last modification date: 2023-09-20)

• Primary citation: Zhou, J.,Lancaster, L.,Donohue, J.P.,Noller, H.F.; How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation.; Science, 345:1188-1191, 2014; PubMed: 25190797; DOI: 10.1126/science.1255030

Experimental method

X-RAY DIFFRACTION (3.8 Å)